| USD ($) $ in Millions | LTM | Dec 31, 2025 | Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | Dec 31, 2017 | Dec 31, 2016 | Dec 31, 2015 | Dec 31, 2014 | Dec 31, 2013 | Dec 31, 2012 | Dec 31, 2011 | Dec 31, 2010 | Dec 31, 2009 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash Flows from Operating Activities | ||||||||||||||||||
Net income | $ 3,169 | $ 18,263 | $ 17,133 | - | ||||||||||||||
Net income from continuing operations | - | - | - | 377 | ||||||||||||||
Adjustments to reconcile net income to net cash provided by operating activities: | ||||||||||||||||||
Amortization | 3,510 | 2,793 | 2,395 | 2,044 | ||||||||||||||
Depreciation | 3,205 | 3,045 | 2,104 | 1,828 | ||||||||||||||
Intangible asset impairment charges | 55 | 55 | 39 | 792 | ||||||||||||||
Depreciation and amortization | - | - | - | - | ||||||||||||||
Income from investments in equity securities, net | (590) | (368) | (14) | (340) | ||||||||||||||
Charge for the acquisition of Prometheus Biosciences, Inc. | - | - | - | 10,217 | ||||||||||||||
Charge for the acquisition of Imago BioSciences, Inc. | - | - | - | 1,192 | ||||||||||||||
Charges for certain research and development asset acquisitions | 13,811 | 0 | 3,456 | 0 | ||||||||||||||
Charge for the acquisition of Peloton Therapeutics, Inc. | - | - | - | - | ||||||||||||||
Charge for future payments related to collaboration license options | - | - | - | - | ||||||||||||||
Provisional charge for one-time transition tax related to the enactment of U.S. tax legislation | - | - | - | - | ||||||||||||||
Charge related to the settlement of worldwide Keytruda patent litigation | - | - | - | - | ||||||||||||||
Foreign currency devaluation related to Venezuela | - | - | - | - | ||||||||||||||
Net charge related to the settlement of Vioxx shareholder class action litigation | - | - | - | - | ||||||||||||||
Gain on divestiture of Merck Consumer Care business | - | - | - | - | ||||||||||||||
Gain on AstraZeneca option exercise | - | - | - | - | ||||||||||||||
Loss on extinguishment of debt | - | - | - | - | ||||||||||||||
In-process research and development impairment charges | - | - | - | - | ||||||||||||||
Gains on distributions from AstraZeneca LP | - | - | - | - | ||||||||||||||
Gain related to Merck/Schering-Plough partnership | - | - | - | - | ||||||||||||||
Gain on disposition of interest in Merial Limited | - | - | - | - | ||||||||||||||
Gain on distribution from AstraZeneca LP | - | - | - | - | ||||||||||||||
Equity income from affiliates | - | - | - | - | ||||||||||||||
Dividends and distributions from equity method affiliates | - | - | - | - | ||||||||||||||
Deferred income taxes | (1,896) | (1,671) | (1,249) | (1,899) | ||||||||||||||
Share-based compensation | 892 | 820 | 761 | 645 | ||||||||||||||
Other | 6 | 511 | 510 | 355 | ||||||||||||||
Taxes paid for Internal Revenue Service settlement | - | - | - | - | ||||||||||||||
Net changes in assets and liabilities: | ||||||||||||||||||
Accounts receivable | (1,090) | (1,090) | (244) | (1,148) | ||||||||||||||
Inventories | (1,180) | (1,180) | (835) | (816) | ||||||||||||||
Trade accounts payable | 110 | 110 | 182 | (380) | ||||||||||||||
Accrued and other current liabilities | (1,841) | (1,841) | (2,328) | 1,783 | ||||||||||||||
Income taxes payable | 137 | 137 | 1,023 | 214 | ||||||||||||||
Noncurrent liabilities | 195 | 195 | (49) | 456 | ||||||||||||||
Other | (3,307) | (3,307) | (1,416) | (2,314) | ||||||||||||||
Net Cash Provided by Operating Activities | 19,967 | 16,472 | 21,468 | - | ||||||||||||||
Net Cash Provided by Operating Activities of Continuing Operations | - | - | - | 13,006 | ||||||||||||||
Cash Flows from Investing Activities | ||||||||||||||||||
Capital expenditures | (3,904) | (4,112) | (3,372) | (3,863) | ||||||||||||||
Purchase of Seagen Inc. common stock | - | - | - | - | ||||||||||||||
Purchases of securities and other investments | (522) | (1,207) | (519) | (955) | ||||||||||||||
Proceeds from sales of securities and other investments | 1,924 | 1,678 | 377 | 1,658 | ||||||||||||||
Proceeds from sale of Seagen Inc. common stock | 0 | 0 | 0 | 1,145 | ||||||||||||||
Acquisition of Peloton Therapeutics, Inc., net of cash acquired | - | - | - | - | ||||||||||||||
Proceeds from sale of interest in Merial Limited | - | - | - | - | ||||||||||||||
Schering-Plough merger, net of cash acquired | - | - | - | - | ||||||||||||||
Acquisition of Verona Pharma plc, net of cash acquired | (18,821) | (10,042) | (746) | 0 | ||||||||||||||
Proceeds from AstraZeneca option exercise | - | - | - | - | ||||||||||||||
Acquisition of Eyebiotech Limited, net of cash acquired | - | 0 | 0 | 0 | ||||||||||||||
Acquisition of Elanco Animal Health Incorporated aqua business | 0 | 0 | (1,303) | - | ||||||||||||||
Acquisition of Harpoon Therapeutics, Inc., net of cash acquired | 0 | 0 | 0 | 0 | ||||||||||||||
Acquisition of MK-1045 from Curon Pharmaceutical | 0 | 0 | (700) | - | ||||||||||||||
Acquisition of Prometheus Biosciences, Inc., net of cash acquired | - | - | - | (10,705) | ||||||||||||||
Acquisition of Prometheus Biosciences, Inc., net of cash acquired | 0 | 0 | (1,344) | (1,327) | ||||||||||||||
Acquisition of Imago BioSciences Inc., net of cash acquired | 0 | 0 | - | - | ||||||||||||||
Divestiture of Merck Consumer Care business, net of cash divested | - | - | - | - | ||||||||||||||
Dispositions of businesses, net of cash divested | - | - | - | - | ||||||||||||||
Acquisition of Bayer AG collaboration rights | - | - | - | - | ||||||||||||||
Cash inflows from net investment hedges | - | - | - | - | ||||||||||||||
Decrease in restricted assets | - | - | - | - | ||||||||||||||
Decrease (Increase) in restricted assets | - | - | - | - | ||||||||||||||
Other | (131) | (58) | (127) | (36) | ||||||||||||||
Net Cash Used in Investing Activities | (27,296) | (13,741) | (7,734) | - | ||||||||||||||
Net Cash Used in Investing Activities of Continuing Operations | - | - | - | (14,083) | ||||||||||||||
Cash Flows from Financing Activities | ||||||||||||||||||
Net change in short-term borrowings | - | - | - | 0 | ||||||||||||||
Net change in short-term borrowings | - | - | - | - | ||||||||||||||
Payments on debt | (1,148) | (2,503) | (1,290) | (1,755) | ||||||||||||||
Proceeds from issuance of debt | 19,836 | 13,880 | 3,599 | 5,939 | ||||||||||||||
Distribution from Organon & Co. | - | - | - | 0 | ||||||||||||||
Purchases of treasury stock | (4,206) | (5,084) | (1,306) | (1,346) | ||||||||||||||
Dividends paid to stockholders | (8,298) | (8,176) | (7,840) | (7,445) | ||||||||||||||
Other dividends paid | - | - | - | - | ||||||||||||||
Proceeds from exercise of stock options | 261 | 92 | 177 | 125 | ||||||||||||||
Other | (227) | (131) | (372) | (328) | ||||||||||||||
Net Cash Used in Financing Activities | 6,170 | (1,922) | (7,032) | - | ||||||||||||||
Effect of Exchange Rate Changes on Cash and Cash Equivalents | - | - | - | - | ||||||||||||||
Net (Decrease) Increase in Cash and Cash Equivalents | - | - | - | - | ||||||||||||||
Net Cash (Used in) Provided by Financing Activities of Continuing Operations | - | - | - | (4,810) | ||||||||||||||
Cash Flows from Discontinued Operations | ||||||||||||||||||
Net cash provided by operating activities | - | - | - | 0 | ||||||||||||||
Net cash used in investing activities | - | - | - | 0 | ||||||||||||||
Net cash used in financing activities | - | - | - | 0 | ||||||||||||||
Net Cash Flows Provided by Discontinued Operations | - | - | - | 0 | ||||||||||||||
Effect of Exchange Rate Changes on Cash, Cash Equivalents and Restricted Cash | (23) | 563 | (293) | 23 | ||||||||||||||
Net Increase (Decrease) in Cash, Cash Equivalents and Restricted Cash | $ (1,182) | $ 1,372 | $ 6,409 | $ (5,864) |